Although the inlet is no longer navigable from the Atlantic Ocean, Nassau Sound is one of the best fishing areas in northeast Florida and home to the state record flounder. Fishing is popular from the George Crady Bridge Fishing Pier and along the shore of Amelia Island State Park. The fishing pier is closed to vehicle traffic and offers the bridge angler a mile of pier to wet their line in hopes of catching the next record fish or tonight's dinner. Many different species of fish can be caught in this area including redfish, whiting, flounder, speckled sea trout, jacks, and tarpon.

Amelia Island State Park is ocated where the Nassau Sound meets the Atlantic Ocean, Amelia Island State Park offers visitors incredible recreational opportunities in a picturesque natural setting. The point at the southern tip of Amelia Island provides a stunning panorama of land and sea.